
운동 피질의 행동 관련 신경 신호는 행동 무관 신호와 뒤섞여 있어 인코딩과 디코딩 메커니즘 연구를 어렵게 한다. 하지만 이 연구에서는 행동 관련 신호와 무관 신호를 정확히 분리하여 분석한 결과, 운동 피질에서 예상치 못한 복잡한 인코딩과 단순한 디코딩 메커니즘을 발견했다.


coremsg

In motor cortex, behaviorally-relevant neural responses are entangled with irrelevant signals, which complicates the study of encoding and decoding mechanisms. It remains unclear whether behaviorally-irrelevant signals could conceal some critical truth. One solution is to accurately separate behaviorally-relevant and irrelevant signals at both single-neuron and single-trial levels, but this approach remains elusive due to the unknown ground truth of behaviorally-relevant signals. Therefore, we propose a framework to define, extract, and validate behaviorally-relevant signals. Analyzing separated signals in three monkeys performing different reaching tasks, we found neural responses previously considered to contain little information actually encode rich behavioral information in complex nonlinear ways. These responses are critical for neuronal redundancy and reveal movement behaviors occupy a higher-dimensional neural space than previously expected. Surprisingly, when incorporating often-ignored neural dimensions, behaviorally-relevant signals can be decoded linearly with comparable performance to nonlinear decoding, suggesting linear readout may be performed in motor cortex. Our findings prompt that separating behaviorally-relevant signals may help uncover more hidden cortical mechanisms.

### Competing Interest Statement

The authors have declared no competing interest.

Revealing unexpected complex encoding but simple decoding mechanisms in motor cortex via separating behaviorally relevant neural signals

운동-피질의-복잡한-인코딩과-단순한-디코딩-메커니즘-과제-관련-신경-신호-추출을-통한-발견


운동 피질의 복잡한 인코딩과 단순한 디코딩 메커니즘 - 과제 관련 신경 신호 추출을 통한 발견
