Keskeiset käsitteet
False-positive mammogram results can lead to a significant decrease in the likelihood of women returning for future routine breast cancer screenings.
Tiivistelmä
The study analyzed over 3 million screening mammograms from more than 1 million women aged 40-73 at nearly 200 facilities between 2005-2017. The researchers classified the mammography results as either true-negative or false-positive, with false-positive results requiring additional imaging, short-interval follow-up, or biopsy recommendations.
The key findings are:
- Nearly 10% of women received false-positive results, with 5.8% needing additional imaging, 2.7% needing short-interval follow-up, and 1.3% recommended for biopsy.
- Women were more likely to return for screening after a true-negative result (76.9%) than after a false-positive result requiring additional imaging (72.4%), short-interval follow-up (54.7%), or biopsy (61.0%).
- Asian and Hispanic/Latinx women who received a false-positive result were much less likely to return for a subsequent screening compared to women of the same groups who received a true-negative result.
- For women with two screenings within 5 years, receiving a false-positive on the second mammogram was linked to a lower likelihood of returning for a third screening, regardless of the first result.
The authors recommend that physicians educate patients about the importance of continued screening after false-positive results, as these are associated with an increased future risk of breast cancer.
Tilastot
Nearly 10.0% (95% CI, 9.1%-10.5%) of women who received screening mammograms got a false-positive result.
5.8% (CI, 5.5%-6.2%) of women with false-positive results needed immediate additional imaging.
2.7% (CI, 2.3%-3.2%) of women with false-positive results needed short-interval follow-up.
1.3% (CI, 1.1%-1.4%) of women with false-positive results were recommended for a biopsy.
76.9% of women returned for screening after a true-negative result.
72.4% of women returned for screening after a false-positive result requiring additional imaging.
54.7% of women returned for screening after a false-positive result requiring short-interval follow-up.
61.0% of women returned for screening after a false-positive result recommended for a biopsy.
Lainaukset
"Physicians should educate their patients about the importance of continued screening after false-positive results, especially given the associated increased future risk for breast cancer."