Modeling Cell Electropermeabilization Using Multiple Traces Formulation and Semi-Implicit Time Coupling

The core message of this article is to simulate the electrical response of multiple disjoint biological 3D cells during the electropermeabilization process using a boundary integral equation approach. The authors employ the Multiple Traces Formulation (MTF) to reduce the volume problem to a system of boundary integral equations, which are then coupled with a time semi-implicit scheme to solve the nonlinear membrane dynamics.