핵심 개념
Atrial high-rate episodes increase mortality risk significantly.
초록
The content discusses how device-detected atrial high-rate episodes (AHRE) are linked to a higher risk of cardiovascular and all-cause mortality, even in patients without prior atrial fibrillation (AF), atrial flutter (AFL), or atrial tachycardia (AT). The study analyzed patients with cardiac implantable electronic devices (CIEDs) and highlighted the importance of screening and monitoring AHRE to prevent adverse outcomes. Key points include:
- AHRE associated with over twice the risk of cardiovascular and all-cause mortality.
- Continuous rhythm monitoring by CIEDs detects asymptomatic episodes of AT/AF.
- Patients with AHRE have a higher risk of clinical AF, heart failure, and thromboembolism.
- Patients with AHRE had significantly higher cardiovascular and all-cause mortality risks.
- Different AHRE burden groups showed varying mortality risks.
- Anticoagulation and additional screening recommended for patients with AHRE.
- Study limitations include unknown confounders and variables.
- Prolonged AHREs considered a precursor of AF, requiring proper evaluation and treatment.
통계
"Patients with AHRE had a significantly higher risk for cardiovascular (hazard ratio [HR], 2.40) and all-cause mortality (HR, 2.31)."
"Patients in the moderate-burden and high-burden groups had higher risks for cardiovascular (HR, 3.64 and HR, 2.33, respectively) and all-cause mortality (HR, 2.76 and HR, 2.26, respectively) than those in the low-burden group."
"Patients with AHRE still had an elevated risk for cardiovascular (HR, 2.41) and all-cause (HR, 2.98) mortality compared with patients without AHRE."
인용구
"Previous studies have confirmed that patients with AHRE are at a higher risk of clinical AF, heart failure, and thromboembolism events."
"Anticoagulation and additional ECG or Holter screening should be considered, based on the patient's AHRE burden and stroke risk factors."
"Prolonged AHREs are a precursor of AF, so patients need to be evaluated and monitored, as well as treated for underlying conditions."