핵심 개념
Ferritin cutoff values significantly impact the diagnosis rate of iron deficiency in primary care settings.
초록
The study investigated how different ferritin cutoff values affect the diagnosis of iron deficiency in primary care. It included 255,351 adult patients in Switzerland and found that:
- A ferritin cutoff of 15 ng/mL was associated with 10.9 iron deficiency diagnoses per 1000 patient-years.
- A cutoff of 30 ng/mL was associated with 29.9 diagnoses per 1000 patient-years.
- A cutoff of 45 ng/mL was associated with 48.3 diagnoses per 1000 patient-years.
The higher the cutoff value, the more cases of iron deficiency were diagnosed, though many of these may have been asymptomatic. Experts recommend a cutoff of 30 ng/mL for certain high-risk populations, but caution that iron supplementation should only be provided to those with true iron deficiency, as indicated by low hemoglobin levels in addition to low ferritin.
통계
Ferritin cutoff of 15 ng/mL was associated with 10.9 iron deficiency diagnoses per 1000 patient-years.
Ferritin cutoff of 30 ng/mL was associated with 29.9 iron deficiency diagnoses per 1000 patient-years.
Ferritin cutoff of 45 ng/mL was associated with 48.3 iron deficiency diagnoses per 1000 patient-years.
인용구
"It is a study to take into account, especially because of the number of patients it includes, and it can guide primary care clinical practice."
"As expected, as the cutoff point increases with respect to ferritin values, the incidence percentages of both iron deficiency and iron-deficiency anemia also increase."
"Establishing the cutoff at 30 ng/mL, in a certain population at risk of iron deficiency or iron-deficiency anemia, may be interesting, for example in women of childbearing age, women with very heavy menstruation, children, frail elderly, people with gastrointestinal bleeding, or those who engage in physical exercise."