
Trientine, a copper chelator, reduces NT-proBNP levels in patients with heart failure and reduced ejection fraction (HFrEF) by restoring intracellular copper, showing promise as a potential treatment option.


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The copper chelator trientine was well tolerated and lowered NT-proBNP levels in patients with heart failure and reduced ejection fraction in a phase 2 study.

Trientine Reduces NT-proBNP in HFrEF: TRACER-HF

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Trientine Reduces NT-proBNP in HFrEF: TRACER-HF Study Results
