The study focused on adults suspected of having celiac disease without IgA deficiency and not on a gluten-free diet. It evaluated the reliability of serum tests for diagnosing celiac disease based on duodenal villous atrophy. The study cohort included 436 adults from 14 centers across four continents. Positive serum tTG-IgA was detected in 83% of participants, with a positive predictive value of 95.9% and a negative predictive value of 90.4%. A no-biopsy approach was deemed safe and reliable for diagnosing celiac disease in adult patients with high serum tTG-IgA.
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by Marilynn Lar... : www.medscape.com 09-19-2023
https://www.medscape.com/viewarticle/996605Daha Derin Sorular