
The cryo-EM structures of the human noradrenaline transporter (NET) provide insights into the molecular mechanisms of substrate recognition, transporter alternating access, and inhibition by antidepressant drugs.


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The cryo-electron microscopy structures of the human noradrenaline transporter in both the apo state and bound to substrates or antidepressant drugs are resolved.

Molecular basis of human noradrenaline transporter reuptake and inhibition - Nature

cryo-em-structures-reveal-molecular-mechanisms-of-human-noradrenaline-transporter-reuptake-and-inhibition-by-antidepressant-drugs


Cryo-EM Structures Reveal Molecular Mechanisms of Human Noradrenaline Transporter Reuptake and Inhibition by Antidepressant Drugs
