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GuideGen: Text-guided Framework for Joint CT Volume and Anatomical Structure Generation


Kernekoncepter
The author presents GuideGen, a framework that generates CT images and tissue masks for abdominal organs and colorectal cancer based on text prompts. By leveraging generative neural models, the pipeline ensures high fidelity and variability in image generation.
Resumé

GuideGen introduces a novel approach to jointly generate CT volumes and anatomical masks guided by text prompts. The framework consists of a Volumetric Mask Sampler for mask generation and a Conditional Image Generator for CT synthesis. Experimental results demonstrate high performance in generating accurate medical images aligned with textual descriptions.

Key points:

  • GuideGen addresses the challenge of generating medical images from text prompts.
  • The framework includes two stages: Volumetric Mask Sampler and Conditional Image Generator.
  • Experiments show high fidelity in generated images and alignment with text conditions.
  • Ablation studies confirm the effectiveness of the proposed modules.
  • Comparison with other methods highlights the superiority of GuideGen in shape accuracy and condition consistency.
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Statistik
"We conduct all experiments on our indoor dataset comprising 3689 cases of abdominal CT scans." "The dataset is randomly split into a training set of 2951 cases, a validation set of 369 cases, and a test set of 369 cases." "Our physical GPU memory limit allows for a batch size of 1 for the first stage model and 2 for the second stage model."
Citater
"No official implementations are found." "Direct application of text prompts on image generation proves to be ineffective." "Our experimental results exhibit high fidelity in our generated image-mask pairs."

Vigtigste indsigter udtrukket fra

by Linrui Dai,R... kl. arxiv.org 03-13-2024

https://arxiv.org/pdf/2403.07247.pdf
GuideGen

Dybere Forespørgsler

How can GuideGen's approach be extended to generate images for other medical conditions

GuideGen's approach can be extended to generate images for other medical conditions by adapting the text prompts and training data to reflect the specific characteristics of those conditions. For instance, if the goal is to generate images related to brain tumors instead of colorectal cancer, the training dataset would need to include CT scans and corresponding masks specific to brain anatomy and tumor locations. The text prompts used in the Volumetric Mask Sampler could be modified to describe features relevant to brain tumors, guiding the generation process towards producing accurate representations. By adjusting the input data and conditioning mechanisms in GuideGen, it can be tailored to various medical scenarios such as lung diseases, cardiovascular conditions, or musculoskeletal disorders. This flexibility allows researchers and practitioners in different medical domains to leverage GuideGen's framework for generating image datasets that align with their specific diagnostic needs.

What are the limitations of using text prompts directly on image generation

The limitations of using text prompts directly on image generation stem from challenges in translating textual descriptions into visual representations accurately. One limitation is ambiguity or subjectivity in language interpretation - different individuals may interpret a given description differently, leading to variations in generated images. Additionally, complex medical terminology or nuanced details present in medical reports may not always translate effectively into precise anatomical structures within generated images. Moreover, relying solely on text prompts for image generation may overlook subtle contextual cues present in imaging data that are crucial for accurate representation. Textual descriptions might lack certain specifics or nuances captured visually by radiologists or clinicians when analyzing medical images. As a result, there could be discrepancies between what is described in text and what should be depicted visually through generated images.

How can the concept of aligning generated images with textual descriptions benefit other fields beyond medical imaging

The concept of aligning generated images with textual descriptions has broader implications beyond medical imaging applications. In fields like design and architecture, this alignment can enhance communication between designers and clients by providing visual representations based on written specifications or briefs. By generating design mock-ups guided by textual descriptions provided by clients or project managers, designers can ensure better understanding and alignment with project requirements. In natural language processing (NLP) tasks such as content creation or storytelling applications, aligning generated visuals with textual narratives can enrich user experiences across digital platforms like websites or mobile apps. By dynamically creating accompanying visuals based on written content inputs from users or automated systems using frameworks similar to GuideGen's approach but adapted for non-medical contexts - new avenues for interactive storytelling emerge where narratives come alive through synchronized imagery.
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