Kernekoncepter
D2-MSNs and D1-MSNs play complementary roles in interval timing, shaping temporal control of action.
Statistik
MSNs encode time across multiple intervals (Emmons et al., 2017; Gouvea et al., 2015; Mello et al., 2015).
D2-MSNs and D1-MSNs exhibit opposing dynamics during interval timing (Alexander and Crutcher, 1990; Cruz et al., 2022; Kravitz et al., 2010).
Disrupting D2-MSNs or D1-MSNs increases response times (De Corte et al., 2019; Drew et al., 2007; Stutt et al., 2023).
Citater
"D2-MSNs and D1-MSNs have opposing patterns of activity with D2-MSNs ramping up and D1-MSNs ramping down." - Study Findings
"Disrupting either D2-MSNs or D1-MSNs increases response times, demonstrating their role in interval timing." - Research Conclusion