Kernekoncepter
Understanding the risk factors and genetic aspects of renal cell carcinoma is crucial for prevention and management.
Resumé
Introduction to the podcast series on renal cell carcinoma with Dr. Monty Pal and Dr. Laura Bukavina.
Dr. Bukavina's background in epidemiology and immunology influences her approach to understanding risk factors for RCC.
Risk factors for RCC include age, gender, genetic mutations, obesity, smoking, diabetes, and hypertension.
Genetic screening is recommended for patients with a family history of kidney cancer or specific risk factors.
Differentiating between benign renal cysts and RCC is essential for proper management and treatment.
The microbiome, including bacteria and fungi, plays a role in modulating treatment responses in kidney cancer.
Collecting stool and urine samples for microbiome research can provide valuable insights into patient responses to therapy.
Dr. Bukavina emphasizes the importance of passion and dedication in pursuing research in kidney cancer, particularly focusing on less studied variants and immunology.
Statistik
"An increase of one point above your average BMI increases your risk of developing kidney cancer by about 20%."
"Smoking causes about a 20% higher risk of development of RCC."
"If you're an insulin-dependent diabetic or if you have hypertension with a higher than 20-point elevation and untreated hypertension, then you're also at about a 10% higher risk of developing kidney cancer down the line."
Citater
"You have to breathe the process. That's what my mentor Phil always says. You have to breathe it. You have to think it. You have to lay in your bed and think about it. That's when you're going to be successful because it's your own." - Dr. Bukavina
"These projects really have to resonate with you. You have to be excited about them and willing to run with them." - Dr. Pal