
초파리 정낭 상피 세포는 유년 호르몬에 의해 활성화되며, 이는 유년 호르몬 수용체 Methoprene-tolerant와 germ cell-expressed에 의해 매개된다.


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Juvenile hormone (JH) is one of the most essential hormones controlling insect metamorphosis and physiology. While it is well known that JH affects many tissues throughout the insects life cycle, the difference in JH responsiveness and the repertoire of JH-inducible genes among different tissues has not been fully investigated. In this study, we monitored JH responsiveness in vivo using transgenic Drosophila melanogaster flies carrying a JH response element-GFP ( JHRE-GFP ) construct. Our data highlight the high responsiveness of the epithelial cells within the seminal vesicle, a component of the male reproductive tract, to JH. Specifically, we observe an elevation in the JHRE-GFP signal within the seminal vesicle epithelium upon JH analog administration, while suppression occurs upon knockdown of genes encoding the intracellular JH receptors, Methoprene-tolerant and germ cell-expressed . Starting from published transcriptomic and proteomics datasets, we next identified Lactate dehydrogenase as a JH-response gene expressed in the seminal vesicle epithelium, suggesting insect seminal vesicles undergo metabolic regulation by JH. Together, this study sheds new light on biology of the insect reproductive regulatory system.

### Competing Interest Statement

The authors have declared no competing interest.

The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster

성체-수컷-초파리-drosophila-melanogaster의-정낭은-성체-호르몬-반응성-조직이다


성체 수컷 초파리 Drosophila melanogaster의 정낭은 성체 호르몬 반응성 조직이다
