In a study published in the journal Chest, researchers analyzed data from 35,654 adults admitted to ICUs between 2010 and 2015. The study focused on the association between the antibiotic combination vancomycin and piperacillin/tazobactam (VPT) and acute kidney injury (AKI) in ICU patients. The primary outcome was AKI, with secondary outcomes including dialysis initiation, dialysis-free survival, and in-hospital mortality. Patients treated with VPT had a significantly higher risk of AKI compared to other antibiotic combinations. The study highlighted the importance of considering patient-specific factors in antibiotic decisions to reduce nephrotoxicity risk and adverse clinical outcomes.
A otro idioma
del contenido fuente
www.medscape.com
Ideas clave extraídas de
by Heidi Splete a las www.medscape.com 04-26-2023
https://www.medscape.com/viewarticle/991218Consultas más profundas