The study delves into the role of neurotensin and thalamic neurons in assigning valence in the brain. Neurotensin levels fluctuate based on reward or punishment learning, impacting behavioral responses. The brain may default to a pessimistic outlook, with negative experiences having a stronger impact than positive ones. The findings suggest that targeting neurotensin and thalamic neurons could be beneficial for treating neuropsychiatric disorders. However, gaps remain in understanding how valence assignments affect anxiety, addiction, and depression.
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by Yasemin Sapl... a las www.quantamagazine.org 09-07-2022
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