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Insufficient Evidence for Lipid Disorder Screening in Children


Concepts de base
Insufficient evidence for lipid disorder screening in children.
Résumé

The US Preventive Services Task Force (USPSTF) finds current evidence lacking to recommend lipid disorder screening in asymptomatic children and those aged 20 or younger. Recommendations focus on heart health promotion through other strategies like obesity screening and tobacco use prevention. The prevalence of conditions like familial hypercholesterolemia (FH) and multifactorial dyslipidemia in children is highlighted, with concerns raised about delayed treatment due to lack of screening. Despite the absence of a clear recommendation, primary care clinicians are advised to promote healthy lifestyle habits. Additional research is called for to assess the effectiveness of lipid screening and treatment in children.

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Stats
The prevalence of FH in US children and adolescents ranges from 0.2% to 0.4%. The prevalence of multifactorial dyslipidemia in children and adolescents ranges from 7.1% to 9.4%.
Citations
"There's just not enough evidence to determine whether or not screening all children for high cholesterol improves their heart health into adulthood." - Katrina Donahue, MD, MPH "Treating FH during childhood slows the progression of vascular finding in atherosclerosis." - Editorial Response

Idées clés tirées de

by Robert Fulto... à www.medscape.com 07-18-2023

https://www.medscape.com/viewarticle/994477
Doctors Still in Dark With Lipid Disorder Screenings in Kids

Questions plus approfondies

How can primary care clinicians effectively address lipid disorders in children without clear screening recommendations?

In the absence of clear screening recommendations for lipid disorders in children, primary care clinicians can still play a crucial role in addressing these issues. They can focus on promoting healthy lifestyle habits such as proper nutrition and physical activity, which are essential for overall cardiovascular health. Clinicians can also consider individual risk factors such as family history of familial hypercholesterolemia (FH) and, in rare cases, order lipid tests for further evaluation. By emphasizing preventive measures and personalized care, clinicians can help mitigate the impact of lipid disorders in children even without specific screening guidelines.

What are the potential consequences of delayed treatment for conditions like familial hypercholesterolemia in children?

Delayed treatment for conditions like familial hypercholesterolemia (FH) in children can have serious consequences on their long-term health. FH is a genetic disorder that leads to abnormally high lipid levels, increasing the risk of premature cardiovascular events such as heart attacks and strokes. If left untreated, FH can progress and accelerate the development of atherosclerosis, a condition that narrows and hardens the arteries, leading to further cardiovascular complications. Early detection and intervention are crucial in managing FH to prevent or delay the onset of cardiovascular events and improve the overall prognosis for affected children.

How can the lack of evidence for lipid disorder screening impact long-term cardiovascular health outcomes in children?

The lack of evidence for lipid disorder screening in children can have significant implications for their long-term cardiovascular health outcomes. Without clear guidelines on screening, there may be missed opportunities to identify and intervene early in conditions like familial hypercholesterolemia (FH) and multifactorial dyslipidemia, which can predispose children to cardiovascular events later in life. Delayed detection and treatment of lipid disorders can lead to the progression of atherosclerosis, increasing the risk of heart attacks, strokes, and other cardiovascular complications in adulthood. The absence of evidence-based screening strategies may result in suboptimal management of lipid disorders, potentially impacting the long-term cardiovascular health outcomes of children.
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