מושגי ליבה
Oral antibiotics are a safe alternative to prolonged IV antibiotics for uncomplicated gram-negative bacteremia.
סטטיסטיקה
Overall, 14.3% of patients on prolonged IV treatment died.
Patients switched to oral antibiotics had a 22% lower risk of death within 90 days.
Patients on oral antibiotics had a 1% lower odds of dying within 90 days.
ציטוטים
"These findings suggest that the mortality associated with early antibiotic stepdown treatment is comparable to that associated with receiving prolonged IV antibiotic treatment for individuals with uncomplicated gram-negative bacteremia." - Study Authors