
Neurodegenerative diseases are characterized by the aggregation of abnormally folded protein filaments in the brain, but a new study has identified the first disease-associated filament composed of two distinct proteins - TDP-43 and annexin A11.


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Proteins TDP-43 and ANXA11 form hybrid filaments in neurons.

Hybrid protein filaments are a surprise twist in neurodegeneration

discovery-of-hybrid-protein-filaments-in-neurodegenerative-diseases-challenges-previous-understanding


Discovery of Hybrid Protein Filaments in Neurodegenerative Diseases Challenges Previous Understanding
