Ectopic Production of Fibroblast Growth Factor 23 Induces Mineral Disturbances, Osteogenic Transdifferentiation, and Cancer-Associated Microcalcifications in the Testis
Testicular microcalcifications can arise due to disturbances in local mineral homeostasis, impaired Sertoli cell function, and aberrant germ cell differentiation, which can lead to osteogenic-like transdifferentiation and deposition of hydroxyapatite.