Core Concepts
The author explores gene regulatory networks to predict therapeutic molecules for Hypopharyngeal Cancer and EGFR-mutated Lung Adenocarcinoma, aiming to improve treatment outcomes.
Abstract
Researchers analyze shared DEGs, construct TF-miRNA networks, identify hub genes, and suggest therapeutic molecules for the two diseases. The study integrates bioinformatics tools to enhance understanding of disease mechanisms.
Stats
605 identical DEGs for Hypopharyngeal cancer and 1062 for EGFR-mutated lung adenocarcinoma were found.
32 common genes identified between the two diseases.
PPI network contains 17 connected genes.