Core Concepts
Increased awareness and early treatment are crucial in preventing fleaborne typhus deaths.
Abstract
The content discusses the rise in fleaborne typhus cases in Los Angeles County, with three associated deaths in 2022. It highlights severe manifestations and the importance of early diagnosis and treatment with doxycycline.
Abstract
- Fleaborne typhus is caused by Rickettsia typhi.
- Case-fatality rate is <1% with doxycycline.
- Cases in Los Angeles County increasing since 2010.
- Three deaths reported in 2022.
Introduction
- Transmitted by infected fleas.
- Oriental rat flea historically the vector.
- Cat flea is the predominant vector in suburban areas.
- Symptoms include fever, rash, hepatitis, and thrombocytopenia.
- Intensive care needed in one third of cases.
- Case-fatality rate <1% with doxycycline.
- Endemic in Los Angeles County.
Stats
"among patients who receive doxycycline, the case-fatality rate is <1%"
"highest number (171) reported during 2022"
"During June–October 2022, Los Angeles County Department of Public Health learned of three fleaborne typhus–associated deaths"
Quotes
"Increased health care provider and public health awareness of the prevalence and severity of fleaborne typhus and of the importance of early doxycycline therapy is essential for prevention and treatment efforts."