Core Concepts
Intermittent fasting combined with early time-restricted eating can impact type 2 diabetes risk.
Abstract
The content discusses a randomized controlled trial involving over 200 individuals at risk of type 2 diabetes. It explores the effectiveness of intermittent fasting (IF) combined with early time-restricted eating in reducing diabetes risk compared to calorie restriction. While the IF intervention showed significant improvements in glucose control at 6 months, adherence to the plan decreased over time. Various experts comment on the study design, feasibility, and potential benefits of different dietary approaches. The study highlights the importance of meal timing and fasting advice in extending health benefits beyond weight loss.
Stats
The IF plus early time-restricted eating intervention was associated with a significant improvement in a key measure of glucose control versus calorie restriction at 6 months.
Less than half of participants were still following the IF plus early time-restricted eating plan at 18 months.
Time-restricted eating has been shown to naturally reduce calorie intake by 300-500 kcal/day.
IF plus early time-restricted eating was associated with greater reductions in postprandial insulin AUC versus calorie restriction at 6 months.
Fatigue was more common with IF plus early time-restricted eating, reported by 56% of participants versus 37% of those following calorie restriction.
Quotes
"Following a time-restricted, IF diet could help lower the chances of developing type 2 diabetes." - Leonie K. Heilbronn, PhD
"In all honesty, I don't think anyone would follow this diet for very long." - Krista Varady, PhD
"These types of diets are much easier to follow and are more likely to produce lasting weight and glycemic control in people with obesity and prediabetes." - Krista Varady, PhD