Researchers conducted a study on PHPT patients undergoing parathyroidectomy surgery to analyze the impact on cognition and sleep quality. Key takeaways include the mediating role of sleep disturbance and latency between PTH levels and cognitive impairment. Post-surgery, cognitive scores improved with reduced PTH levels, but sleep quality remained unaffected. The study emphasizes the importance of monitoring PTH levels, cognition, and sleep quality in PHPT patients for potential interventions to enhance cognitive preservation. The research involved a retrospective review of medical records from PHPT patients treated with PTX and controls, assessing sleep quality and cognition pre- and postoperatively. Higher PTH levels were associated with poorer sleep quality and cognition, with sleep latency mediating the effect of PTH on cognitive function.
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by Miriam E. Tu... at www.medscape.com 04-03-2023
https://www.medscape.com/viewarticle/990389Deeper Inquiries