Core Concepts
Nitrous oxide shows promise in managing pain during prostate biopsies.
Abstract
The study presented at the 2023 American Urological Association meeting explores the use of nitrous oxide for pain management during prostate biopsies. Researchers found that patients who self-administered nitrous oxide had lower post-biopsy pain scores and reduced odds of experiencing pain during the procedure compared to those who received oxygen as a placebo. The study highlights the potential benefits of using nitrous oxide in outpatient urologic procedures, providing a more comfortable experience for patients.
Highlights
- Nitrous oxide is a minimal sedative that shows promise in managing pain during prostate biopsies.
- Patients who self-administered nitrous oxide had lower post-biopsy pain scores and reduced odds of experiencing pain during the procedure.
- The Nitrouseal system allows patients to adjust gas levels for optimal sedation without the need for anesthesia personnel.
- Nitrous oxide may improve patient experience and willingness to undergo repeat biopsies.
- Transperineal biopsies may offer advantages over transrectal biopsies, especially in reducing discomfort associated with the procedure.
Stats
"At concentrations of less than 50%, nitrous oxide is classified as a minimal sedative, making it a promising option for many urologic outpatient procedures such as prostate biopsies," said Heidi Rayala, MD, PhD.
"Patients in the SANO group had a smaller change in post-biopsy pain score (Visual Analog Scale for pain, 0.43 vs 1.03; P = .03) and lower odds of experiencing pain during the procedure (odds ratio, 0.45; CI, 0.21-0.97; P = .04)."
Quotes
"This study adds to the evidence to support adjunct use of mild inhalational anesthetics and analgesics during prostate biopsies to improve the patient experience of the procedure." - Stephen McCombie, MD