Core Concepts
Universal CVD risk prediction model shows good performance in both ASCVD and non-ASCVD patients.
Stats
Over a median follow-up of 18.9 years, 3209 ARIC participants (35%) developed MACE.
Hazard ratio C-statistic for the universal prediction model: 0.692 for ASCVD, 0.748 for non-ASCVD.
Over a median follow-up of 13.7 years in the MESA cohort, 12% of participants developed MACE.
Quotes
"The findings support the importance of established predictors for classifying long-term CVD risk in both primary and secondary prevention settings."
"The universal risk assessment approach is conceptually promising."
"Careful cost-benefit analyses may also be needed before the risk model can be used in clinical settings."