Core Concepts
Atopic dermatitis increases GBS colonization risk in pregnant women.
Abstract
The study suggests that pregnant women with atopic dermatitis (AD) are more likely to be colonized with group B streptococcus (GBS) compared to others. Researchers conducted a cross-sectional study using an administrative database to explore this association. Key findings include:
- AD may be a risk factor for maternal carriage of GBS.
- Women with AD had higher odds of asthma and seasonal allergies.
- GBS was reported in 20.6% of the cohort.
- Pregnant women with AD had a higher prevalence of GBS colonization.
- Individuals with AD might have deficiencies in host defenses against pathogens.
- Antibiotic use in AD treatment could alter the resident microbiome.
- The study acknowledges limitations due to the reliance on an administrative database.
Adam Friedman highlighted the importance of screening pregnant AD patients for GBS and raised questions about potential changes in clinical practices. The study does not provide definitive answers but prompts further inquiry into screening and decolonization regimens for pregnant women with AD.
Stats
"GBS was reported in 20.6% of the cohort."
"Among the women with AD, 24.1% had GBS, compared with 20.51% of the women without AD (P <.0001)."
"The OR of asthma was 1.08 (95% CI, 1.06-1.10) among women with GBS."
Quotes
"AD could be a risk factor for maternal carriage of GBS."
"Individuals with AD frequently receive antibiotics as part of their AD treatment and this might alter their resident microbiome."
"Pregnant women should be screened for GBS regardless, but maybe more attention or counseling can be offered to AD patients about the importance of screening."