Core Concepts
Untreated adult patients with Thyroid Hormone Alpha Resistance exhibit distinct clinical features and may benefit from early diagnosis and treatment.
Stats
"During childhood and adolescence, short stature, short limbs, metacarpals, and phalanges, and delayed bone age maturation were observed."
"FT4/FT3 ratio and reverse T3 were low."
"All individuals complained of tiredness, constipation, and low mood."
Quotes
"We suggest that THRA analysis should be performed in patients with specific clinical features, as treatment in early childhood may improve outcomes."