Core Concepts
Possible association between Dubowitz syndrome and Pyoderma Gangrenosum.
Abstract
Standalone Note:
Abstract and Introduction
Dubowitz syndrome is a rare genetic disorder with growth retardation, microcephaly, and increased cancer risk.
Pyoderma Gangrenosum (PG) is an autoinflammatory disorder causing painful ulcers on the skin.
Case Presentation
50-year-old female with Dubowitz syndrome developed painful ulcerative lesions.
Diagnosis of PG made after biopsy and treated with wound dressings and glucocorticoids.
Significant improvement in clinical picture after 7 weeks of therapy.
Conclusions
First reported case suggesting a link between Dubowitz syndrome and PG.
Introduction
Dubowitz syndrome is a rare genetic disorder with various clinical manifestations.
PG is a neutrophilic dermatosis with inflammatory and ulcerative skin lesions.
Unusual case of PG in a patient with Dubowitz syndrome reported.
Stats
Dubowitz syndrome is characterized by growth retardation, microcephaly, and increased cancer risk.
PG presents with inflammatory and ulcerative lesions on the skin.
More than 50% of PG patients have comorbid diseases.
Quotes
"This case report is the first to suggest a possible association between Dubowitz syndrome and PG."