Core Concepts
Biologic adjuvants show promise in treating ankle cartilage injuries.
Stats
"It has been estimated that up to 50% of patients who sustain an ankle sprain and up to 88% of patients who sustain an ankle fracture have a concomitant cartilage injury."
"The most commonly used biologic adjuncts include concentrated bone marrow aspirate (CBMA), platelet-rich plasma (PRP), hyaluronic acid (HA), and micronized adipose tissue (MAT)."
Quotes
"The secretome's immunomodulatory, anti-apoptotic, angiogenic, and anti-fibrotic effects are critical in maintaining joint homeostasis."
"Historically, the elements required for cartilage regeneration included growth factors, a proper scaffold, and mesenchymal stem cells (MSCs)."