Sign In

Atrial Fibrillation Risk with Gabapentin Use

Core Concepts
Gabapentin can induce atrial fibrillation in young individuals.
Abstract and Introduction Gabapentin is commonly used for neuropathic pain and seizures. Evidence suggests an increased risk of atrial fibrillation with gabapentin. Case Presentation Case of a young African American male developing atrial fibrillation after gabapentin use. Normal lab results but with a patent foramen ovale. Treatment involved diltiazem, apixaban, and cardioversion. Conclusion Gabapentin's growing use requires awareness of potential adverse effects. Atrial fibrillation can be a side effect in young individuals.
"Gabapentin can be associated with increased risk of atrial fibrillation." "Transthoracic and transesophageal echocardiography showed a patent foramen ovale."
"New-onset atrial fibrillation could be induced by gabapentin in young individuals."

Key Insights Distilled From

by Sung Hwan Pa... at 08-08-2023
Atrial Fibrillation Induced By Gabapentin

Deeper Inquiries

How does the risk of atrial fibrillation with gabapentin compare to other medications

Gabapentin has been associated with an increased risk of atrial fibrillation, particularly in older patients with comorbidities predisposing them to arrhythmias. Compared to other medications, the risk of atrial fibrillation with gabapentin appears to be relatively low but significant, especially in certain patient populations. While the most common side effects of gabapentin are related to the central nervous system, its potential impact on the cardiovascular system, specifically in terms of atrial fibrillation, should not be overlooked.

What are the implications of this case for the use of gabapentin in young patients

This case highlights the importance of considering the potential cardiovascular effects of gabapentin, even in young patients without significant comorbidities. Healthcare providers should be vigilant when prescribing gabapentin to young individuals, especially when initiating therapy or increasing the dosage. Monitoring for signs of atrial fibrillation and other cardiovascular complications should be part of the routine assessment for patients receiving gabapentin, regardless of age. Additionally, further research is needed to better understand the mechanisms underlying gabapentin-induced atrial fibrillation in young patients.

How can healthcare providers balance the benefits and risks of gabapentin therapy in light of these findings

Healthcare providers must carefully weigh the benefits and risks of gabapentin therapy, particularly in light of its potential to induce atrial fibrillation in young individuals. When considering gabapentin for a patient, providers should conduct a thorough assessment of the patient's cardiovascular risk factors, including age, comorbidities, and family history of arrhythmias. Shared decision-making with the patient is crucial to ensure that the potential benefits of gabapentin outweigh the risks, taking into account alternative treatment options and individual patient preferences. Regular monitoring for cardiovascular side effects, such as atrial fibrillation, should be incorporated into the treatment plan to promptly identify and manage any adverse events.