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Higher-Order Networks Representation and Learning: A Comprehensive Survey


Core Concepts
The authors explore the evolution of network data from dyadic to higher-order structures, focusing on motifs, simplicial complexes, and hypergraphs. They aim to provide a detailed overview of advanced techniques in higher-order network analysis.
Abstract
The content delves into the evolution of network data representation from traditional dyadic graphs to higher-order structures like motifs, simplicial complexes, and hypergraphs. It discusses the significance of studying higher-order patterns in various scientific domains and provides insights into modeling interactions among more than two entities. The paper also covers applications such as sensor coverage, disease detection, mobility analysis, network modeling, and tools for network analysis. Traditional network models enriched with additional attributes like weights and signs have paved the way for studying higher-order networks. The exploration of motifs in biological networks and brain networks has revealed functional insights related to specific functionalities. Simplicial complexes offer a generalized approach beyond traditional graphs by representing relationships using k-simplices. Hypergraphs extend the concept further by allowing edges to be subsets of vertices. The use cases span across various fields including sensor coverage problems modeled using simplicial complexes, disease detection through point cloud representations, mobility analysis using topological signatures over trajectories, and network modeling with configuration models. Tools like Hodge Laplacian for random walks on edges in simplicial complexes and spectral clustering demonstrate advancements in edge-based analyses. Overall, the content provides a comprehensive overview of higher-order network analysis techniques and their diverse applications across different domains.
Stats
In 2002, Shen-Orr et al. distinguished three families of motifs in Escherichia coli (E. coli) directed transcriptional network. First-order random walks are not able to describe network flows. For a 2-complex both nodes and edges have to be specified. The Rips complex is defined as a simplicial complex whose simplices are tuples of nodes whose pairwise Euclidean distances are within a certain threshold. The Simplicial Contagion Model is a more flexible fit for more complex diseases with varying infection probabilities of different orders.
Quotes
"Network data has become widespread, larger, and more complex over the years." - Hao Tian and Reza Zafarani

Key Insights Distilled From

by Hao Tian,Rez... at arxiv.org 03-01-2024

https://arxiv.org/pdf/2402.19414.pdf
Higher-Order Networks Representation and Learning

Deeper Inquiries

How can the study of motifs in biological networks contribute to understanding gene expression?

In biological networks, studying motifs can provide valuable insights into gene expression. Network motifs are specific subpatterns or subgraphs that occur more frequently than expected in a network. In the context of biological networks, these motifs can represent functional units or building blocks of transcriptional regulation networks. By analyzing the frequency and distribution of these motifs within biological networks, researchers can uncover important relationships between genes and their regulatory elements. For example, Shen-Orr et al. distinguished three families of motifs in Escherichia coli (E. coli) directed transcriptional network: feedforward loops, single input modules, and dense overlapping regulons. Each motif family is associated with specific functionalities related to gene expression regulation. The presence and abundance of these motifs can indicate how certain genetic pathways are regulated and coordinated within the cell. Furthermore, by simulating evolutionary processes on electronic combinatorial logic circuits initiated by random wiring patterns, researchers have shown that evolved networks under modularly varying goals exhibit higher modularity levels and better adaptability to changing environmental conditions. This suggests that motif-based structures play a crucial role in optimizing genetic regulatory mechanisms for efficient gene expression. Studying network motifs in biological networks not only helps identify key functional components but also provides a deeper understanding of how genes interact with each other to regulate various cellular processes such as growth, development, and response to external stimuli.

What are some practical applications of sensor coverage problems modeled using simplicial complexes?

Sensor coverage problems modeled using simplicial complexes have several practical applications across different fields: Wireless Sensor Networks: In wireless sensor networks where sensors monitor physical environments or detect events like fires or intrusions, simplicial complexes help analyze sensor coverage areas efficiently. By representing sensors as vertices connected through edges based on signal strength or proximity thresholds, researchers can identify uncovered regions (holes) in real-time monitoring systems. Healthcare Monitoring: Simplicial complex models are used for patient monitoring systems where wearable sensors track vital signs or movement patterns continuously. Environmental Monitoring: For ecological studies involving habitat monitoring or wildlife tracking using sensor nodes placed strategically across an area. Smart Cities: In urban planning scenarios where sensors collect data on traffic flow patterns or air quality levels for city management purposes. 5Emergency Response Systems: During natural disasters like earthquakes or floods when rapid deployment of sensing devices is required for assessing damage areas accurately.

How do hypergraphs differ from simplicial complexes in terms of representing relationships among entities?

Hypergraphs differ from simplicial complexes primarily in how they represent relationships among entities: 1Edge Structure: Hypergraphs allow edges to connect any subset of vertices rather than pairs as seen in traditional graphs/simplicial complexes. Simplices (basic units) form the structure in simplicial complexes while hyperedges define connections directly between multiple vertices without restrictions on size. 2Complexity: Hypergraphs tend to be more complex due to their high-dimensional edge space compared to simpler structures found in simplicial complexes. 3Representation: While both representations capture higher-order interactions beyond pairwise relationships, hypergraphs focus on capturing all possible subsets involved simultaneously whereas simplicials maintain inclusivity requiring all faces/sub-simplices be included along with primary ones. 4Applications: Hypergraph theory has theoretical foundations but fewer direct practical applications compared with simplcial complex modeling which finds use cases ranging from biology & healthcare analysis mobility studies & social network analysis due its simplicity & interpretability features..
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