Concetti Chiave
The use of TKIs has revolutionized CML treatment, impacting fertility and pregnancy considerations.
Statistiche
"about 1 in 100,000 pregnancies is associated with CML"
"the greatest thing that's happened in the past 25 years is TKIs"
"the platelet count then overshoots, so you end up with an even higher platelet count than you started with"
"the jury is still out a little bit, but increasingly, we think that the TKIs are probably safe in the third trimester"
"the incidence of congenital abnormalities was much higher than what you would see in the healthy population"
Citazioni
"The greatest thing that's happened in the past 25 years is TKIs."
"The story isn't over just yet."
"The end result is that blast crisis has a dismal prognosis."
"I think many listeners or even us we've heard colleagues say, 'pregnancy and CML? That's not going to be successful.' No, we need to dismiss these ideas."
"I've heard women come to me very despondent."