핵심 개념
Genetic therapies are revolutionizing neurology practice.
초록
The content discusses the impact of genetic therapies on neurology clinics, focusing on conditions like Charcot-Marie-Tooth (CMT) neuropathy. Dr. Nicolas Madigan highlights the potential of genetic treatments for neuromuscular diseases, emphasizing the importance of genetic testing and counseling in patient care. The landscape of treatments for CMT is explored, including drug combinations, gene replacement strategies, and CRISPR-Cas9 approaches. The need for genetic counselors to support patients through testing and treatment decisions is also addressed.
통계
"In a city of about a million people, there will be 100-800 patients with one of these disorders," said Dr. Madigan.
"the genetic tests costs $300 versus tens of thousands of dollars for IVIG," said Dr. Madigan.
"Dr. Madigan's group recently reviewed 286 CMT clinical trials published between 1999 and 2022,".
인용구
"I think we will very soon be in a position to tell these patients that they might actually have a better treatment outcome with a genetic treatment than if they had a sporadic or inflammatory disorder," - Dr. Madigan
"I think it's working extremely well, and I would encourage all practices to begin to explore those options moving forward," - Dr. Madigan