The study explores how prefrontal-hippocampal theta synchrony influences memory-guided choices. Initiating trials during strong synchrony led to better performance on working memory tasks. Optogenetic activation of the ventral midline thalamus modulated theta rhythms, highlighting the importance of neural circuit dynamics in decision-making processes.
The research delves into the intricate interactions between brain regions during memory-guided choices. Strong prefrontal-hippocampal theta coherence was associated with improved task performance, shedding light on the neural mechanisms underlying cognitive processes. The findings suggest that manipulating oscillatory dynamics through brain machine interfacing could offer a promising approach to enhance cognitive functions.
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by Stout,J. J.,... 게시일 www.biorxiv.org 04-02-2023
https://www.biorxiv.org/content/10.1101/2023.04.02.535279v4더 깊은 질문