The American Society of Retina Specialists (ASRS) reported six cases of occlusive retinal vasculitis post pegcetacoplan injection. The etiology remains unclear, with evolving patient outcomes. Pegcetacoplan, targeting complement factor 3 in drusen, was approved for geographic atrophy treatment. Trials showed low rates of intraocular inflammation but no retinal vasculitis. Apellis Pharmaceuticals is investigating the cases, emphasizing the importance of sterile practices during injection.
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by Richard Mark... om www.medscape.com 07-18-2023
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