The study aimed to assess the prevalence of axial spondyloarthritis (axSpA) in two Canadian cohorts of patients with psoriasis, uveitis, or colitis who presented with chronic undiagnosed back and/or buttock pain.
In the SASPIC-1 cohort, axSpA diagnoses were made in 46.7% of patients with psoriasis, 61.6% with uveitis, and 46.8% with colitis. In the SASPIC-2 cohort, the rates were 23.5%, 57.9%, and 23.3%, respectively.
Being positive for the HLA-B27 gene was linked to the presence of axSpA in 56%-88% of patients across both cohorts. However, musculoskeletal clinical features were not helpful in differentiating between patients with and without axSpA.
The study found that MRI of the sacroiliac joints was indicative of axSpA in a significantly greater number of patients diagnosed with axSpA compared to those not diagnosed.
The authors conclude that patients with chronic back pain and extra-articular features related to axSpA should be referred to a rheumatologist, as MRI is a more accurate diagnostic method than clinical features alone.
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by Edited Shrab... om www.medscape.com 08-14-2024
https://www.medscape.com/viewarticle/diagnosing-chronic-back-pain-psoriasis-uveitis-and-colitis-2024a1000ey0Diepere vragen