
세포막의 높은 수투과성으로 인해 거대분자 응축이 세포 내 삼투압 변화를 완충할 수 없다.


coremsg

[Watson et al . (2023][1], Macromolecular condensation buffers intracellular water potential, Nature 623: 842-852) have proposed that the reversible formation and disassembly of molecular condensates could act as the primary buffer of cytoplasmic osmolality in the face of changes in extracellular osmolality. In this communication, I show using well-established membrane biophysics, that the water permeability of plasma membranes is likely to overwhelm any cytoplasmic water buffers.

### Competing Interest Statement

The authors have declared no competing interest.

 [1]: #ref-27

Macromolecular condensation is unlikely to buffer intracellular osmolality

세포-내-삼투압-완충에-거대분자-응축이-불가능할-것으로-보임


세포 내 삼투압 완충에 거대분자 응축이 불가능할 것으로 보임
