Conceitos essenciais
PCOS can lead to cognitive deficits and reduced brain integrity.
Resumo
TOPLINE:
PCOS linked to lower cognitive test scores and reduced brain tissue integrity.
METHODOLOGY:
Data from a 30-year study on 900 women, 66 with PCOS.
Tests on verbal learning, memory, processing speed, executive function, attention, and cognitive control.
TAKEAWAY:
PCOS individuals showed poorer memory, attention, and verbal ability.
Lower white matter integrity in PCOS linked to cognitive deficits.
IN PRACTICE:
Concerns raised about cognitive effects of PCOS on public health.
SOURCE:
Study led by Heather G. Huddleston, MD, published in Neurology.
LIMITATIONS:
PCOS diagnosis based on androgen levels and self-reporting, potential misclassification.
DISCLOSURES:
Study funded by the University of California, San Francisco.
Estatísticas
Individuals with PCOS had worse memory, attention, and verbal ability scores than those without the disorder.
MRI scans showed that those with PCOS had lower white matter integrity, indicating cognitive deficits.
Up to 10% of women may be affected by PCOS, with implications for public health.
Citações
"This report of midlife cognition in PCOS raises a new concern about another potential comorbidity for individuals with this common disorder."