Основные понятия
Bariatric surgery is an effective long-term strategy for controlling high blood pressure in obese individuals.
Аннотация
The GATEWAY trial followed 100 adults with obesity and uncontrolled hypertension over 5 years, comparing the outcomes of bariatric surgery and medication alone. Key highlights include:
- Bariatric surgery led to lower BMI and reduced antihypertensive medication use.
- Patients who underwent surgery maintained normal blood pressure more effectively.
- The study emphasizes the importance of treating obesity to address cardiovascular diseases.
- Results were published in the Journal of the American College of Cardiology.
- Surgery group showed significant reductions in antihypertensive medication use and higher rates of hypertension remission.
- Ambulatory BP monitoring data revealed similar BP profiles between surgery and medication groups.
- Surgery group had lower rates of resistant hypertension and atrial remodeling.
- Study limitations include a small sample size and single-center design.
- Authors stress the importance of addressing obesity to reduce hypertension rates.
Статистика
"After 5 years, BMI was 28.01 kg/m2 for those who had surgery vs 36.40 kg/m2 for those on medication alone (P <.001)."
"Patients who underwent RYGB had an 80.7% reduction in the number of antihypertensive medications they were taking while maintaining BP < 140/90 mm Hg compared with a 13.7% reduction in those on medication alone."
"The rate of hypertension remission (controlled BP without medication) was nearly 20-fold higher in the surgery group than in the medication only group (46.9% vs 2.4%; P < .001)."
Цитаты
"Bariatric and metabolic surgery can be very effective in the treatment of patients with obesity and hypertension in the long term." - Carlos Aurelio Schiavon, MD
"Taken together, these results support the long-term effective role of bariatric surgery in reducing the burden of hypertension and related polypharmacy." - Study Authors