
The ABC transporter KpsMT, associated with the KpsE and KpsD subunits, is responsible for the translocation of capsular polysaccharides (CPSs) across the inner bacterial membrane in Gram-negative bacteria.


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An ensemble of cryo-electron microscopy structures of the KpsMT ABC transporter in complex with the KpsE co-polymerase and a glycolipid substrate reveal how capsular polysaccharides are recognized and translocated across bacterial cell membranes.

Molecular insights into capsular polysaccharide secretion - Nature

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Structural and Functional Insights into the Secretion Mechanism of Capsular Polysaccharides in Bacteria
