E. coli ClpB Exhibits Processive Unfolding and Translocation of Stably Folded Protein Substrates
E. coli ClpB, a protein disaggregase, can processively unfold and translocate stably folded protein substrates through its hexameric ring structure, with a kinetic step-size of ~60 amino acids and an overall rate of ~0.9 amino acids per second.