
Brainstem Dbh+ neurons are a key node in the neural circuit controlling allergen-induced airway hyperreactivity, a hallmark of asthma.


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Mapping a full allergen circuit from the lung to the brainstem and back, repeated exposure of mice to inhaled allergen activated the nuclei of solitary tract neurons in a mast cell-, interleukin-4- and vagal nerve-dependent manner.

Brainstem Dbh+ neurons control allergen-induced airway hyperreactivity - Nature

brainstem-dopamine-beta-hydroxylase-positive-neurons-control-allergen-induced-airway-hyperreactivity-in-asthma


Brainstem Dopamine Beta-Hydroxylase Positive Neurons Control Allergen-Induced Airway Hyperreactivity in Asthma
