
The author presents a novel couple-close method for constructing semisaturated ring systems from dual radical precursors, addressing the limitations of current synthetic methods and enabling the creation of diverse saturated ring types with potential pharmaceutical applications.


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A couple-close approach used to build semisaturated ring systems from dual radical precursors allows sampling of regions of underexplored chemical space, leading to an annulation that can be used for late-stage functionalization of pharmaceutical scaffolds.

Couple-close construction of polycyclic rings from diradicals - Nature

innovative-approach-to-building-polycyclic-rings-from-diradicals


Innovative Approach to Building Polycyclic Rings from Diradicals
