Основні поняття
Obesity may worsen menopausal symptoms and limit hormone therapy effectiveness.
Анотація
The study presented at the Menopause Society highlighted the impact of obesity on menopausal symptoms and hormone therapy effectiveness. Key findings include:
- Women with obesity experience more severe menopausal symptoms.
- Hormone therapy may be less effective in women with obesity.
- Adipose tissue acting as a heat insulator could reduce hormone therapy efficacy.
- Women with obesity were less likely to see symptom improvement with hormone therapy.
- Diverse patient populations need better care and counseling for menopausal symptoms.
- Providers may undertreat women with obesity due to fear and comorbidities.
- Study limitations include small size and inability to control for other medications.
Статистика
More than 40% of women over age 40 in the United States have obesity.
Obesity was defined as having a body mass index (BMI) of 30 kg/m2 or greater.
Women with obesity were much less likely to see a satisfying reduction in their menopausal symptoms than women without obesity (odds ratio 0.07, 95% confidence interval, 0.01-0.64; P = .006).
Цитати
"Obesity may worsen a woman's menopausal symptoms and limit the amount of relief she gets from hormone therapy." - Dr. Pershad
"My guess is people are afraid. Women with obesity also may have other comorbidities." - Dr. Faubion