Основні поняття
Partial breast irradiation is recommended over whole breast irradiation for appropriately selected patients with early-stage breast cancer.
Анотація
The American Society for Radiation Oncology (ASTRO) has updated its clinical practice guideline on partial breast irradiation for women with early-stage invasive breast cancer or ductal carcinoma in situ (DCIS). The new 2023 recommendations are based on recent clinical trial data that show no significant differences in overall survival, cancer-free survival, and recurrence between partial and whole breast irradiation. The guideline strongly recommends partial breast irradiation for patients with favorable clinical features and tumor characteristics, providing detailed recommendations on techniques and best practices for delivering partial breast irradiation.
Key Highlights:
- Updated guideline based on recent clinical trial data
- No significant differences in outcomes between partial and whole breast irradiation
- Strong recommendation for partial breast irradiation in patients with favorable features
- Detailed recommendations on techniques and best practices
Статистика
"There have been more than 10,000 women included in these randomized controlled trials, with 10 years of follow-up showing equivalency in tumor control between partial breast and whole breast radiation for appropriately selected patients." - Simona Shaitelman, MD
"The guideline, developed in collaboration with the American Society of Clinical Oncology and the Society of Surgical Oncology, has been endorsed by the Canadian Association of Radiation Oncology, the European Society for Radiotherapy and Oncology, and the Royal Australian and New Zealand College of Radiologists."
Цитати
"These data should be driving a change in practice, and partial breast radiation should be a larger part of the dialogue when we consult with patients on decisions about how best to treat their early-stage breast cancer." - Simona Shaitelman, MD
"We hope that by laying out the evidence from these major trials and providing guidance on how to administer partial breast radiation, the guideline can help more oncologists feel comfortable offering this option to their patients as an alternative to whole breast radiation." - Janice Lyons, MD