The study on postinfectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) aimed to delve into the underlying pathophysiology of ME/CFS. Key findings include autonomic dysfunction, immune dysregulation, and metabolic abnormalities. The study compared 17 individuals with PI-ME/CFS to 21 healthy volunteers, revealing distinct somatic and cognitive complaints in ME/CFS. Physical deconditioning was noted as a consequence, not the source, of the condition. The study highlighted the need for disease-modifying therapies for ME/CFS, as current treatments are only symptomatic. Various postinfectious syndromes, including ME/CFS, share similar symptoms and pathophysiology, suggesting overlapping triggers and mechanisms. The study emphasized the importance of understanding the pathophysiology to develop effective therapies for ME/CFS.
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by Miriam E. Tu... lúc www.medscape.com 02-22-2024
https://www.medscape.com/viewarticle/deep-phenotyping-identifies-abnormalities-me-cfs-2024a10003icYêu cầu sâu hơn