
The human brain vasculature exhibits extensive molecular heterogeneity across development, adulthood, and various vascular-dependent central nervous system pathologies.


coremsg

Endothelial cells from vascular-dependent central nervous system (CNS) diseases reveal reactivated fetal pathways, display common hallmarks of disease — including a partial loss of arteriovenous specification and CNS-specific properties as well as an upregulation of MHC class II receptors — and play a key role in the human brain neurovascular unit across development, adulthood and disease.

Single-cell atlas of the human brain vasculature across development, adulthood and disease - Nature

comprehensive-single-cell-analysis-of-the-human-brain-vasculature-across-development-adulthood-and-pathological-conditions


Comprehensive Single-cell Analysis of the Human Brain Vasculature Across Development, Adulthood, and Pathological Conditions
