
The cryogenic electron microscopy structure of the Fcε–FcεRI complex reveals the molecular basis of FcεRI assembly and the asymmetric architecture of the FcRγ dimer, which is crucial for the signaling mechanisms of FcεRI and other immune receptors.


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A study presents high-resolution cryogenic electron microscopy structures detailing how the elements of FcεRI assemble and how this receptor complex interacts with the target immunoglobulin E.

Structural insights into the high-affinity IgE receptor FcεRI complex - Nature

structural-insights-into-the-assembly-and-signaling-mechanisms-of-the-high-affinity-ige-receptor-fcεri-complex


Structural Insights into the Assembly and Signaling Mechanisms of the High-Affinity IgE Receptor FcεRI Complex
