
The La protein, an endogenous small RNA-binding exonuclease protection factor, can significantly enhance the efficiency of prime editing across various approaches, edit types, and cell types.


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Genome-scale genetic screens identify the small RNA-binding protein La as a strong mediator of prime editing.

Improving prime editing with an endogenous small RNA-binding protein - Nature

enhancing-prime-editing-efficiency-through-harnessing-an-endogenous-rna-binding-protein


Enhancing Prime Editing Efficiency through Harnessing an Endogenous RNA-Binding Protein
