
Neurons undergo DNA damage and repair processes mediated by TLR9 during memory formation.


coremsg

Learning results in persistent double-stranded DNA breaks, nuclear rupture and release of DNA fragments and histones within hippocampal CA1 neurons that, following TLR9-mediated DNA damage repair, results in their recruitment to memory circuits.

Formation of memory assemblies through the DNA-sensing TLR9 pathway - Nature

formation-of-memory-assemblies-through-the-dna-sensing-tlr9-pathway


Formation of Memory Assemblies Through the DNA-Sensing TLR9 Pathway
