Core Concepts
Fiber supplement intake during pregnancy can reduce the risk of gestational diabetes and preterm birth in women with high insulin resistance.
Abstract
Researchers conducted a study on pregnant women with high insulin resistance to assess the impact of a fiber supplement on gestational diabetes and preterm birth.
Key Takeaways
High insulin resistance women showed improved glucose metabolism and reduced risk of gestational diabetes and preterm birth with fiber supplement intake.
The intervention did not affect lipid profiles or other outcomes.
Why This Matters
Gestational diabetes poses risks for maternal and perinatal complications and future type 2 diabetes.
High TyG index in early pregnancy is linked to gestational diabetes development.
Enhancing glucose metabolism in high TyG index women may prevent gestational diabetes.
Study Design
295 women with a TyG index ≥ 8.5 before 20 weeks' gestation were randomly assigned.
Women received oral dietary fiber powder or usual care during weeks 20-24.
Participants underwent glucose tolerance tests and additional assessments.
Key Results
Fiber supplement group had lower gestational diabetes incidence and blood glucose levels.
No significant differences in other parameters between groups.
Women receiving the supplement had longer gestational age and lower preterm birth rates.
Limitations
Small sample size and single-center study.
Short duration of the dietary fiber intervention.
Disclosures
Study had no commercial funding.
Authors had no disclosures.
Stats
"The incidence of gestational diabetes among women in the group who ingested the fiber supplement was 11.2%, significantly less than the 23.7% rate among women who served as controls."
"Mean gestational age at delivery among women who received the fiber supplement was 39.07 weeks, significantly greater than the 38.58-week average among the controls."
"The incidence of preterm delivery at less than 37 weeks was 2.3% among women who used the fiber supplement, significantly less than the 9.4% rate among the controls."
Quotes
"Improving glucose metabolism in women with a high TyG index during pregnancy might help prevent gestational diabetes."